产品货号:
Z16800
中文名称:
ERAB/HSD17B10抗体
英文名称:
Anti-ERAB/HSD17B10 Antibody (Center)
产品规格:
50μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ERAB/HSD17B10 Antibody (Center) |
指标别名 | 17 beta HSD 10;17b HSD10;ABAD;CAMR;DUPXp11.22;ERAB;HADH2;HCD2;HSD17B10;MHBD;MRPP2;MRX17;MRX31;MRXS10;SCHAD;SDR5C1;Type II HADH;XH98G2 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,FCM,IHC,IF |
基因名称 | HSD17B10 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | This HSD17B10 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 140-172 amino acids from the Central region of human HSD17B10. |
计算分子量 | 27kDa |
成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
保存条件 | Maintain refrigerated at 2~8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
背景资料 | Functions in mitochondrial tRNA maturation.Part of mitochondrial ribonuclease P,an enzyme composed of MRPP1/TRMT10C,MRPP2/HSD17B10 and MRPP3/KIAA0391,which cleaves tRNA molecules in their 5'-ends.Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone.Catalyzes the third step in the beta-oxidation of fatty acids.Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids.Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids.By interacting with intracellular amyloid-beta,it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD). |
Uniprot ID | Q99714 |
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